Comparing the Efficacy of Alvogyl and Zinc Oxide Eugenol Dressing For the Treatment of Dry Socket: A Double Blind Randomised Study

Background: The most common unpleasant post operative complication following extraction of permanent teeth is Dry socket. The primary goal of treatment for dry socket is pain relief. Local dressings will do better pain relief and faster healing. Aim: To compare the effectiveness of Alvogyl and Zinc oxide eugenol dressings placed intra alveolar for the management of dry socket. Methods:All the patient who underwent extraction of teeth and who satisfied the inclusion and exclusion criteria were included in the study. Patients who were diagnosed to suffer from dry socket were randomly allocated to two groups name Group A (Zinc oxide Eugenol) and Group B (Alvogyl). Pain relief was compared between the two groups. Results: In all the level of time assessed Alvogyl showed the statistically significant difference in relieving pain than Zinc oxide eugenol dressings. Alvogyl required less number of dressings when compared to zinc oxide eugenol. Conclusion: Alvogyl is far better than the Zinc oxide eugenol dressing for providing pain relief in dry socket.

Bioremediation of Chromium, Nickel and Zinc in Electroplating Effluent by Escherichia coli.

Effluent samples from an electroplating industry located at Madurai, India were collected and analysed for chosen physico-chemical parameters. Among the heavy metals tested, zinc exhibited highest level with 739 ppm with a pH of 4.83. The bacterial strain isolated from the effluent contaminated site was identified as Escherichia coli and it was subjected to 15, 20 and 25% of effluent in minimal broth for 20 days. Optical density and pH changes were recorded daily and the levels of chromium, nickel and zinc were analysed after ten and twenty days of treatment. Significant reduction in the level of zinc was observed and the results are discussed.

Interaction of two LAC repressor protein segments with polynucleotides.

The interaction of the oligopeptides Ala-Gln-GIn-Leu-Ala-Gly-OH and Gln-Leu- Ala-Gly-OMe corresponding, respectively, to the sequence 53–58 and 55–58 of lac repressor protein with four polynucleotides was studied. The two peptides did not interact with poly dA. poly dT, poly d(A-T).poly d(A-T) or poly d(A-G).poly d(C-T). But they interacted in a characteristic way with poly d(A-C). poly d (G-T), the sequences of which are in abundance in the lac operator region. Both the peptides stabilised the melting of poly d (A-C). poly d (G-T) at a peptide to nucleotide ratio (P/N) of 4; at lower ratios, they destabilised the DNA slightly. The circular dichroism of the alternating polynucleotide with CAC/GTG sequences was perturbed by both the oligopeptides. The hexapeptide at a P/N of 4 caused the transformation of the Bform circular dichroism spectrum to a new state, characterised by strong 220 and 240 nm bands, and a rather weak long wavelength spectrum.

α -D-Galactose-specific lectin from jack fruit (A rtocarpus integra) seed.

An α-D-galactose-specific lectin from the seeds of jack fruit (Artocarpus integra) has been isolated in pure form by affinity chromatography on immobilised guar gum (a galactomannan). The lectin is shown to be a glycoprotein containing 3% carbohydrate and having a molecular weight of 39,500 as determined by gel filtration. Sodium dodecyl sulphate gel electrophoresis revealed a single polypeptide of 10,500 dalton, indicating that the native lectin is a tetrarner of identical subunits. The hemagglutinating activity of the lectin towards erythrocytes of all blood groups is found to be the same.